David’s current positions include Professor of Kidney Medicine at University College London, Honorary Consultant Nephrologist at the Royal Free London NHS Foundation Trust and Honorary Professorial Fellow of the George Institute for Global Health, Sydney, Australia. He is a Clinician Scientist with an interest in the complications of chronic kidney disease, specifically those that increase the burden of cardiovascular disease and/or accelerate progression of kidney failure. He has contributed to the development and running of several large-scale clinical trials involving patients with chronic kidney disease including SHARP, EVOLVE and CREDENCE. He is currently co-chief investigator of the DAPA-CKD study. Locally, he heads the clinical research team at the Centre for Nephrology, Royal Free Hospital in London. He has been involved in Clinical Practice Guideline Development for several organisations, most recently for Kidney Disease: Improving Global Outcomes (KDIGO), of which he is currently co-chair. He has served terms as President of the UK Renal Association, Chair of the UK Renal Registry and Associate Editor of Nephrology Dialysis Transplantation (NDT).